Col1a1tm14(CAG-Sox2)Nki
Targeted Allele Detail
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| Symbol: |
Col1a1tm14(CAG-Sox2)Nki |
| Name: |
collagen, type I, alpha 1; targeted mutation 14, The Netherlands Cancer Institute |
| MGI ID: |
MGI:6158303 |
| Synonyms: |
LSL-Sox2 |
| Gene: |
Col1a1 Location: Chr11:94827050-94843868 bp, + strand Genetic Position: Chr11, 59.01 cM, cytoband D
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| Alliance: |
Col1a1tm14(CAG-Sox2)Nki page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:236715
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
FVB
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| Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Mutation details: RMCE introduced into the 3' UTR the targeting construct Sox2-frt-invCAG that contains and inverted CAG promoter, the Sox2 gene, an IRES sequence and a CFP reporter gene. Cre-mediated recombination is required to achieve expression.
(J:236715)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Col1a1 Mutation: |
160 strains or lines available
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| Original: |
J:236715 Ferone G, et al., SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin. Cancer Cell. 2016 Oct 10;30(4):519-532 |
| All: |
2 reference(s) |
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Analysis Tools
