Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Sod1em1Rhbr
Name:	superoxide dismutase 1, soluble; endonuclease-mediated mutation 1, Robert Brown Jr
MGI ID:	MGI:6157439
Synonyms:	Sod1A4V
Gene:	Sod1  Location: Chr16:90017650-90023221 bp, + strand  Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
Alliance:	Sod1em1Rhbr page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Humanized sequence) Mutations:    Insertion, Nucleotide substitutions   Mutation details: CRISPR/Cas9 methodologies were used to introduce a 2 bp base pair mutation (CG>TC) resulting in an A4V point mutation. The mutation is associated with Amyotrophic Lateral Scleroris. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sod1 Mutation:	37 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)