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Pou6f1tm1.1Arenk
Targeted Allele Detail
Summary
Symbol: Pou6f1tm1.1Arenk
Name: POU domain, class 6, transcription factor 1; targeted mutation 1.1, Benjamin Arenkiel
MGI ID: MGI:6153800
Synonyms: POU6f1 cKO
Gene: Pou6f1  Location: Chr15:100473199-100497865 bp, - strand  Genetic Position: Chr15, 56.35 cM
Alliance: Pou6f1tm1.1Arenk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:258273
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsThe targeting vector contains a loxP site downstream of exon 1, and an FRT-flanked neomycin cassette followed by a loxP site downstream of exon 11. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:258273)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pou6f1 Mutation:  21 strains or lines available
References
Original:  J:258273 McClard CK, et al., POU6f1 Mediates Neuropeptide-Dependent Plasticity in the Adult Brain. J Neurosci. 2018 Feb 7;38(6):1443-1461
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory