Cav1tm1.1Madp
Targeted Allele Detail
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Symbol: |
Cav1tm1.1Madp |
Name: |
caveolin 1, caveolae protein; targeted mutation 1.1, Miguel Angel del Pozo |
MGI ID: |
MGI:6150433 |
Synonyms: |
Y14F |
Gene: |
Cav1 Location: Chr6:17306387-17341323 bp, + strand Genetic Position: Chr6, 7.73 cM, cytoband A2
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Alliance: |
Cav1tm1.1Madp page
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Germline Transmission: |
Earliest citation of germline transmission:
J:232807
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Not Specified) |
Mutations: |
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Insertion, Nucleotide substitutions
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Mutation details: A Y14F mutation was introduced in exon 2 and a floxed neo cassette was inserted in intron 1 via homologous recombination. Cre-mediated recombination removed the neo cassette allowing expression of the mutant protein.
(J:232807)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cav1 Mutation: |
29 strains or lines available
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Original: |
J:232807 Schonle A, et al., Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells. Blood. 2016 Apr 14;127(15):1930-9 |
All: |
2 reference(s) |
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