Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Relatm1.1Ukl
Name:	v-rel reticuloendotheliosis viral oncogene homolog A (avian); targeted mutation 1.1, Ulf Klein
MGI ID:	MGI:6148061
Gene:	Rela  Location: Chr19:5687511-5698158 bp, + strand  Genetic Position: Chr19, 4.34 cM, cytoband B1-3
Alliance:	Relatm1.1Ukl page

Germline Transmission:	Earliest citation of germline transmission: J:244578
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Sequence encoding a promoterless eGFP minigene, a loxP site and the PGKneo cassette was inserted upstream of exon 1 of the targeted gene; another loxP site followed by the PGK promoter was inserted downstream of exon 1. The entire targeted region was flanked by FRT sites. Cre-mediated recombination removes exon 1. (J:244578)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rela Mutation:	24 strains or lines available

Original:	J:244578 Badran YR, et al., Human RELA haploinsufficiency results in autosomal-dominant chronic mucocutaneous ulceration. J Exp Med. 2017 Jul 03;214(7):1937-1947
All:	2 reference(s)