Axltm1.1Cvro
Targeted Allele Detail
|
|
| Symbol: |
Axltm1.1Cvro |
| Name: |
AXL receptor tyrosine kinase; targeted mutation 1.1, Carla V Rothlin |
| MGI ID: |
MGI:6147861 |
| Synonyms: |
Axlfl |
| Gene: |
Axl Location: Chr7:25456698-25488130 bp, - strand Genetic Position: Chr7, 14.02 cM, cytoband A3-B1
|
| Alliance: |
Axltm1.1Cvro page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:234329
|
| Parent Cell Line: |
Not Specified (ES Cell)
|
| Strain of Origin: |
C57BL/6
|
|
| Allele Type: |
|
Targeted (Conditional ready, No functional change) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: A loxP site was inserted upstream of exon 9. A FRT site, a loxP site, a neomycin resistance gene, a FRT site, and a third loxP site were inserted downstream of exon 10. Flp-mediated recombination removed the selection cassette, leaving exons 9-10 floxed.
(J:234329)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Axl Mutation: |
58 strains or lines available
|
|
| Original: |
J:234329 Schmid ET, et al., AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity. Elife. 2016;5:e12414 |
| All: |
5 reference(s) |
|
Analysis Tools
