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Bhlhe40tm1Ukbh
Targeted Allele Detail
Summary
Symbol: Bhlhe40tm1Ukbh
Name: basic helix-loop-helix family, member e40; targeted mutation 1, Ujjal K Bhawal
MGI ID: MGI:6147782
Synonyms: DEC1-
Gene: Bhlhe40  Location: Chr6:108637590-108643886 bp, + strand  Genetic Position: Chr6, 49.85 cM, cytoband E-F1
Alliance: Bhlhe40tm1Ukbh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:233166
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The entire coding region, exons 1 to 5, was replaced with a neomycin cassette. (J:233166)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bhlhe40 Mutation:  50 strains or lines available
References
Original:  J:233166 Fujita Y, et al., Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice. Biochem Biophys Res Commun. 2016 Jan 15;469(3):477-82
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory