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Rfx1tm1Tqi
Targeted Allele Detail
Summary
Symbol: Rfx1tm1Tqi
Name: regulatory factor X, 1 (influences HLA class II expression); targeted mutation 1, Tao Qi
MGI ID: MGI:6147372
Synonyms: Rfx1flox
Gene: Rfx1  Location: Chr8:84793463-84823621 bp, + strand  Genetic Position: Chr8, 40.28 cM
Alliance: Rfx1tm1Tqi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:234925
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 3 and a loxP site and a neomycin cassette were inserted downstream of exon 4 resulting in floxed exons 3-4. (J:234925)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rfx1 Mutation:  46 strains or lines available
References
Original:  J:234925 Wang B, et al., RFX1 maintains testis cord integrity by regulating the expression of Itga6 in male mouse embryos. Mol Reprod Dev. 2016 Jul;83(7):606-14
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory