Summary | Mutation origin | Mutation description | Tumor data | Find Mice (IMSR) | References

Symbol:	Serpinb5tm1.1Shsh
Name:	serine (or cysteine) peptidase inhibitor, clade B, member 5; targeted mutation 1.1, Shijie Sheng
MGI ID:	MGI:6119743
Synonyms:	Maspinflox
Gene:	Serpinb5  Location: Chr1:106788905-106811078 bp, + strand  Genetic Position: Chr1, 50.34 cM
Alliance:	Serpinb5tm1.1Shsh page

Germline Transmission:	Earliest citation of germline transmission: J:239395
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The targeting construct contained loxP sites flanking exon 4 and a FRT-flanked PGK-neomycin selection cassette inserted between exons 3 and 4. Flp-mediated recombination removed the neomycin cassette. (J:239395)

List all tumor models in MMHCdb carrying Serpinb5tm1.1Shsh

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpinb5 Mutation:	34 strains or lines available

Original:	J:239395 Dzinic SH, et al., An Essential Role of Maspin in Embryogenesis and Tumor Suppression. Cancer Res. 2017 Feb 15;77(4):886-896
All:	1 reference(s)