Bgntm1.1Debi
Targeted Allele Detail
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| Symbol: |
Bgntm1.1Debi |
| Name: |
biglycan; targeted mutation 1.1, David E Birk |
| MGI ID: |
MGI:6119512 |
| Synonyms: |
Bgnflox |
| Gene: |
Bgn Location: ChrX:72527208-72539539 bp, + strand Genetic Position: ChrX, 37.33 cM, cytoband B
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| Alliance: |
Bgntm1.1Debi page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:256331
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| Parent Cell Line: |
JM8A3.N1 (ES Cell)
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| Strain of Origin: |
C57BL/6N-Atm1Brd
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| Allele Type: |
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Targeted (Conditional ready) |
| Mutation: |
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Insertion
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Mutation details: The IKMC targeting vector PG00154_Z_5_F10 was used to insert a construct containing an FRT site, lacZ gene, loxP site, neo gene, FRT site and loxP site upstream of exon 4 and a third loxP site downstream of exon 4. Flp mediated recombination removed the lacZ and neo genes leaving exon 4 floxed.
(J:256331)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Bgn Mutation: |
8 strains or lines available
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| Original: |
J:256331 Robinson KA, et al., Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons. Matrix Biol. 2017 Dec;64:81-93 |
| All: |
1 reference(s) |
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Analysis Tools
