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Stat1m3Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Stat1m3Btlr
Name: signal transducer and activator of transcription 1; mutation 3, Bruce Beutler
MGI ID: MGI:6113472
Synonyms: rollo
Gene: Stat1  Location: Chr1:52119440-52161865 bp, + strand  Genetic Position: Chr1, 26.81 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced C to A transversion at base pair 52,153,923 (v38) on chromosome 1, or base pair 34,486 in the GenBank genomic region NC_000067. The mutation corresponds to residue 2,270 in the mRNA sequence NM_001205313 within exon 22 of 25 total exons. The mutation results in substitution of tyrosine 651 for a premature stop codon (Y651*) in the protein. (J:254835)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stat1 Mutation:  24 strains or lines available
References
Original:  J:254835 Nair-Gill E, et al., Mutagenetix entry for rollo. MGI Direct Data Submission. 2018;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory