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Targeted Allele Detail
Symbol: Esyt2tm1.1Sud
Name: extended synaptotagmin-like protein 2; targeted mutation 1.1, Thomas C Sudhof
MGI ID: MGI:6101168
Synonyms: 2EF
Gene: Esyt2  Location: Chr12:116281196-116391050 bp, + strand  Genetic Position: Chr12, 62.65 cM, cytoband F2
Germline Transmission:  Earliest citation of germline transmission: J:236019
Parent Cell Line:  ART B6-3, B6-3 (ES Cell)
Strain of Origin:  C57BL/6NTac
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
Mutation detailsFlp-mediated recombination of Esyt2 resulted in the removal of the neomycin selection cassette and mutated exon 10, leaving the endogenous exon 10 flanked by loxP sites. (J:236019)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esyt2 Mutation:  1 strain or line available
Original:  J:236019 Sclip A, et al., Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction. PLoS One. 2016;11(6):e0158295
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory