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Ddx27tm1Wcs
Targeted Allele Detail
Summary
Symbol: Ddx27tm1Wcs
Name: DEAD box helicase 27; targeted mutation 1, William C Skarnes
MGI ID: MGI:5903510
Synonyms: Dxd27tm2
Gene: Ddx27  Location: Chr2:166857233-166876865 bp, + strand  Genetic Position: Chr2, 87.22 cM
Alliance: Ddx27tm1Wcs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:243553
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Duplication, Insertion
 
Mutation detailsA splice acceptor, hygromycin resistance gene, GFP reporter gene, polyadenylation sequence and kanamycin resistance gene were inserted upstream of the critical exon 7, duplicating genomic sequences contained in the vector. (J:243553)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddx27 Mutation:  36 strains or lines available
References
Original:  J:243553 Fisher CL, et al., An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Nucleic Acids Res. 2017 Dec 1;45(21):e174
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory