Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Elf3tm1Mote
Name:	E74-like factor 3; targeted mutation 1, Miguel Otero
MGI ID:	MGI:5818512
Synonyms:	Elf3f
Gene:	Elf3  Location: Chr1:135181312-135186210 bp, - strand  Genetic Position: Chr1, 58.42 cM, cytoband F
Alliance:	Elf3tm1Mote page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	B6(Cg)-Tyrc-2J/J

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The L1L2_Bact_P cassette was inserted at position 135258154 of Chromosome 1 (intron 1) upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 135254725 (intron 8). FLP-mediated recombination excised the FRT-flanked neomycin/lacZ cassette, leaving exons 2-8 flanked by loxP sites. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Elf3 Mutation:	38 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	2 reference(s)