Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Mef2cem1Blk
Name:	myocyte enhancer factor 2C; endonuclease-mediated mutation 1, Brian L Black
MGI ID:	MGI:5792882
Synonyms:	Mef2cF1delta
Gene:	Mef2c  Location: Chr13:83652153-83815199 bp, + strand  Genetic Position: Chr13, 43.68 cM
Alliance:	Mef2cem1Blk page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Modified regulatory region) Mutation:    Intragenic deletion     CRISPR/Cas9 technology targeted the F1 enhancer for deletion in intron 3. (J:224213)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mef2c Mutation:	33 strains or lines available

Original:	J:224213 Hu J, et al., Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway. Development. 2015 Aug 15;142(16):2775-80
All:	1 reference(s)