Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tph1tm1Lex
Name:	tryptophan hydroxylase 1; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID:	MGI:5775285
Gene:	Tph1  Location: Chr7:46294065-46321961 bp, - strand  Genetic Position: Chr7, 30.43 cM
Alliance:	Tph1tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:227247
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     Deletion of coding exons 3-6. (J:227247)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tph1 Mutation:	39 strains or lines available

Original:	J:227247 Brommage R, et al., High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes. Bone Res. 2014;2:14034
All:	1 reference(s)