Runx2tm1.1Cmg
Targeted Allele Detail
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| Symbol: |
Runx2tm1.1Cmg |
| Name: |
runt related transcription factor 2; targeted mutation 1.1, Cecilia Giachelli |
| MGI ID: |
MGI:5770389 |
| Synonyms: |
Runx2f |
| Gene: |
Runx2 Location: Chr17:44806873-45125518 bp, - strand Genetic Position: Chr17, 21.33 cM
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| Alliance: |
Runx2tm1.1Cmg page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:223299
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
C57BL/6 x 129S/SvEv
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 4. Am FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and left exon 4 floxed.
(J:223299)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Runx2 Mutation: |
42 strains or lines available
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| Original: |
J:223299 Lin ME, et al., Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice. Am J Pathol. 2015 Jul;185(7):1958-69 |
| All: |
3 reference(s) |
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Analysis Tools
