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Prkd1tm1.1Ltg
Targeted Allele Detail
Summary
Symbol: Prkd1tm1.1Ltg
Name: protein kinase D1; targeted mutation 1.1, Michael Leitges
MGI ID: MGI:5755123
Gene: Prkd1  Location: Chr12:50388014-50695881 bp, - strand  Genetic Position: Chr12, 21.78 cM, cytoband C1
Alliance: Prkd1tm1.1Ltg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:221790
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP sites was inserted upstream of exon 3 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 4 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:221790)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkd1 Mutation:  55 strains or lines available
References
Original:  J:221790 Liou GY, et al., Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia. Nat Commun. 2015;6:6200
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory