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Sat1tm1.1Kzah
Targeted Allele Detail
Summary
Symbol: Sat1tm1.1Kzah
Name: spermidine/spermine N1-acetyl transferase 1; targeted mutation 1.1, Kamyar Zahedi
MGI ID: MGI:5751527
Synonyms: SSAT-CkoNeo-/FLP-
Gene: Sat1  Location: ChrX:153996128-153999445 bp, - strand  Genetic Position: ChrX, 72.38 cM, cytoband F3-F4
Alliance: Sat1tm1.1Kzah page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:229304
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsAn FRT- and loxP-site flanked neomycin resistance cassette was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exons 1 through 3 floxed. (J:229304)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sat1 Mutation:  7 strains or lines available
References
Original:  J:229304 Zahedi K, et al., Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1;303(5):G546-60
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory