Dp(16Dyrk1a-B3galt5)5TybEmcf
Targeted Allele Detail
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| Symbol: |
Dp(16Dyrk1a-B3galt5)5TybEmcf |
| Name: |
duplication, Chr 16, Victor Tybulewicz and Elizabeth M C Fisher 5 |
| MGI ID: |
MGI:5703806 |
| Synonyms: |
Dp(16)5TybEmcf, Dp5Tyb |
| Gene: |
Dp(16Dyrk1a-B3galt5)5TybEmcf Location: unknown Genetic Position: Chr16, Syntenic
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| Germline Transmission: |
Earliest citation of germline transmission:
J:227899
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| Parent Cell Line: |
HM-1 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd-Hprtb-m3
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| Allele Type: |
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Targeted |
| Mutations: |
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Duplication, Insertion
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Dp(16Dyrk1a-B3galt5)5TybEmcf involves 38 genes/genome features (Gm15317, Gm15341, Gm22745 ...)
View all
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Mutation details: MICER vectors MHPP432c09 (16:94538615-16:94546849 Mb; mouse assembly GRCm38/mm10) located between Dscr3 and Dyrk1a and MHPN235b18 (16:96327324-16:96331804 Mb) located between B3galt5 and Igsf5 were subjected to cre-mediated recombination to duplicate the sequence flanked by loxP sites.
(J:227899)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Carrying any Dp(16Dyrk1a-B3galt5)5TybEmcf Mutation: |
1 strain or line available
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| Original: |
J:227899 Lana-Elola E, et al., Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. Elife. 2016 Jan 14;5:e11614 |
| All: |
2 reference(s) |
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Analysis Tools
