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Dp(16Mir802-Vps26c)4TybEmcf
Targeted Allele Detail
Summary
Symbol: Dp(16Mir802-Vps26c)4TybEmcf
Name: duplication, Chr 16, Victor Tybulewicz and Elizabeth M C Fisher 4
MGI ID: MGI:5703804
Synonyms: Dp(16)4TybEmcf, Dp(16Mir802-Dscr3)4TybEmcf, Dp4Tyb
Gene: Dp(16Mir802-Vps26c)4TybEmcf  Location: unknown  Genetic Position: Chr16, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:227899
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Mutation
description
Allele Type:    Targeted
Mutations:    Duplication, Insertion
  Dp(16Mir802-Vps26c)4TybEmcf involves 33 genes/genome features (Gm41500, Gm23062, Gm22344 ...) View all
 
Mutation detailsAn un-specified MICER vector and MHPP432c09 (16:94538615-16:94546849 Mb; mouse assembly GRCm38/mm10) located between Dscr3 and Dyrk1a were subjected to cre-mediated recombination to duplicate the sequence flanked by loxP sites. (J:227899)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Dp(16Mir802-Vps26c)4TybEmcf Mutation:  2 strains or lines available
References
Original:  J:227899 Lana-Elola E, et al., Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. Elife. 2016 Jan 14;5:e11614
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory