Myf6tm1.1(cre/Esr1*)Cklr
Targeted Allele Detail
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Symbol: |
Myf6tm1.1(cre/Esr1*)Cklr |
Name: |
myogenic factor 6; targeted mutation 1.1, Charles Keller |
MGI ID: |
MGI:5688769 |
Synonyms: |
Myf6CreER |
Gene: |
Myf6 Location: Chr10:107328709-107330584 bp, - strand Genetic Position: Chr10, 55.96 cM
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Alliance: |
Myf6tm1.1(cre/Esr1*)Cklr page
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Germline Transmission: |
Earliest citation of germline transmission:
J:214957
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Myf6tm1.1(cre/Esr1*)Cklr expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Myf6 (MGI:97253) |
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Mutation details: Homologous recombination in ES cells inserted an IRES-creERTM-FRT-Neo-FRT sequence into the 3' UTR following the stop codon in exon 3. Flp-mediated recombination removed the selection cassette.
(J:214957)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Myf6
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Myf6 Mutation: |
19 strains or lines available
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Original: |
J:214957 Abraham J, et al., Lineage of origin in rhabdomyosarcoma informs pharmacological response. Genes Dev. 2014 Jul 15;28(14):1578-91 |
All: |
1 reference(s) |
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