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Egr2tm1.1Wjl
Targeted Allele Detail
Summary
Symbol: Egr2tm1.1Wjl
Name: early growth response 2; targeted mutation 1.1, Warren J Leonard
MGI ID: MGI:5662541
Synonyms: Egr2f
Gene: Egr2  Location: Chr10:67371305-67378018 bp, + strand  Genetic Position: Chr10, 34.96 cM, cytoband B5
Alliance: Egr2tm1.1Wjl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:216751
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site and FRT flanked Ncol-pgk-neo cassette were inserted upstream of exon 3 and a loxP site was inserted at the end of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:216751)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Egr2 Mutation:  31 strains or lines available
References
Original:  J:216751 Du N, et al., EGR2 is critical for peripheral naive T-cell differentiation and the T-cell response to influenza. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16484-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory