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Onecut2tm1.1Xmu
Targeted Allele Detail
Summary
Symbol: Onecut2tm1.1Xmu
Name: one cut domain, family member 2; targeted mutation 1.1, Xiuqian Mu
MGI ID: MGI:5661977
Synonyms: Oc2flox
Gene: Onecut2  Location: Chr18:64473098-64531559 bp, + strand  Genetic Position: Chr18, 37.33 cM, cytoband D3
Alliance: Onecut2tm1.1Xmu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:216471
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of the transcription start site and a loxP-FRT-neo-FRT cassette was inserted in intron 1 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:216471)
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Onecut2 Mutation:  20 strains or lines available
References
Original:  J:216471 Sapkota D, et al., Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4086-95
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory