Ccna2tm1.1Kald
Targeted Allele Detail
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Symbol: |
Ccna2tm1.1Kald |
Name: |
cyclin A2; targeted mutation 1.1, Philipp Kaldis |
MGI ID: |
MGI:5637531 |
Synonyms: |
A2flox |
Gene: |
Ccna2 Location: Chr3:36619014-36626299 bp, - strand Genetic Position: Chr3, 17.67 cM
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Alliance: |
Ccna2tm1.1Kald page
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Germline Transmission: |
Earliest citation of germline transmission:
J:212546
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Parent Cell Line: |
S1B6 (ES Cell)
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Strain of Origin: |
129S1/SvImJ or C57BL/6J
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the neo cassette.
(J:212546)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ccna2 Mutation: |
15 strains or lines available
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Original: |
J:212546 Gopinathan L, et al., Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis. Cancer Res. 2014 Jul 15;74(14):3870-9 |
All: |
3 reference(s) |
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