Nkx2-5tm1.1Ccai
Targeted Allele Detail
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| Symbol: |
Nkx2-5tm1.1Ccai |
| Name: |
NK2 homeobox 5; targeted mutation 1.1, Chen-Leng Cai |
| MGI ID: |
MGI:5629737 |
| Synonyms: |
Nkx2.5GFP-3XFLAG |
| Gene: |
Nkx2-5 Location: Chr17:27057638-27063962 bp, - strand Genetic Position: Chr17, 13.6 cM
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| Alliance: |
Nkx2-5tm1.1Ccai page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:212423
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The targeting construct introduced at the exon 1 translation initiation site a loxP site, nucleosome localized GFP reporter gene with 4 polyadenylation sequences (H2B-GFP-4XpA), loxP site, FRT-flanked neomycin resistance cassette and 3 FLAG tags. Flp-mediated recombination removed the selection cassette.
(J:212423)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Nkx2-5 Mutation: |
21 strains or lines available
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| Original: |
J:212423 Zhang L, et al., Mesodermal Nkx2.5 is necessary and sufficient for early second heart field development. Dev Biol. 2014 Jun 1;390(1):68-79 |
| All: |
2 reference(s) |
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Analysis Tools
