Pou4f2tm1.1(cre)Tcba
Targeted Allele Detail
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Symbol: |
Pou4f2tm1.1(cre)Tcba |
Name: |
POU domain, class 4, transcription factor 2; targeted mutation 1.1, Tudor Constantin Badea |
MGI ID: |
MGI:5629683 |
Synonyms: |
Brn3bCKOCre |
Gene: |
Pou4f2 Location: Chr8:79159639-79163274 bp, - strand Genetic Position: Chr8, 36.99 cM, cytoband F1-F5
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Alliance: |
Pou4f2tm1.1(cre)Tcba page
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Germline Transmission: |
Earliest citation of germline transmission:
J:215125
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, Recombinase) |
Mutation: |
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Insertion
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Pou4f2tm1.1(cre)Tcba expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pou4f2 (MGI:102524) |
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Mutation details: The targeting construct introduced into the 3'UTR three polyadenylation squences, a RoxP site, a cre recombinase gene and an FRT-flanked neomycin resistance cassette. An additional RoxP site was inserted upstream of the translation start site. Flp-mediated recombination removed the selection cassette and left the coding sequence plus 3 polyadenylation sequence flanked by RoxP sites.
(J:215125)
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Generation of the Pou4f2tm1.1(cre)Tcba allele |
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pou4f2
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pou4f2 Mutation: |
7 strains or lines available
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Original: |
J:215125 Sajgo S, et al., Dre - Cre sequential recombination provides new tools for retinal ganglion cell labeling and manipulation in mice. PLoS One. 2014;9(3):e91435 |
All: |
1 reference(s) |
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