Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ebf1tm2.1Mbu
Name:	early B cell factor 1; targeted mutation 2.1, Meinrad Busslinger
MGI ID:	MGI:5617009
Synonyms:	Ebh1fl
Gene:	Ebf1  Location: Chr11:44508144-44898918 bp, + strand  Genetic Position: Chr11, 26.45 cM
Alliance:	Ebf1tm2.1Mbu page

Germline Transmission:	Earliest citation of germline transmission: J:183852
Parent Cell Line:	A9 (ES Cell)
Strain of Origin:	(C57BL/6 x 129P2/OlaHsd)F1

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: Exon 6 was replaced with a floxed cDNA encoding exons 6-16, the 3' UTR and a 6x polyA signal, followed by exon 6 fused to a GFP reporter gene and an FRT flanked neo selection cassette in the inverse orientation. Flp mediated recombination removed the neo cassette. (J:183852)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ebf1 Mutation:	73 strains or lines available

Original:	J:183852 Vilagos B, et al., Essential role of EBF1 in the generation and function of distinct mature B cell types. J Exp Med. 2012 Apr 9;209(4):775-92
All:	2 reference(s)