Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ebf1tm1.1Mbu
Name:	early B cell factor 1; targeted mutation 1.1, Meinrad Busslinger
MGI ID:	MGI:5617008
Synonyms:	Ebh1ihCd2
Gene:	Ebf1  Location: Chr11:44508144-44898918 bp, + strand  Genetic Position: Chr11, 26.45 cM
Alliance:	Ebf1tm1.1Mbu page

Germline Transmission:	Earliest citation of germline transmission: J:183852
Parent Cell Line:	A9 (ES Cell)
Strain of Origin:	(C57BL/6 x 129P2/OlaHsd)F1

Allele Type:    Targeted (No functional change, Reporter) Mutation:    Insertion   Mutation details: An IRES-human CD2 reporter construct and a floxed neo cassette were inserted in the 3' untranslated region via homologous recombination. Cre mediated recombination removed the neo cassette. (J:183852)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf1 Mutation:	73 strains or lines available

Original:	J:183852 Vilagos B, et al., Essential role of EBF1 in the generation and function of distinct mature B cell types. J Exp Med. 2012 Apr 9;209(4):775-92
All:	2 reference(s)