Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Six2tm1(EGFP/cre)Phoh
Name:	sine oculis-related homeobox 2; targeted mutation 1, Peter Hohenstein
MGI ID:	MGI:5578005
Synonyms:	Six2GCiP
Gene:	Six2  Location: Chr17:85991705-85995702 bp, - strand  Genetic Position: Chr17, 55.72 cM
Alliance:	Six2tm1(EGFP/cre)Phoh page

Germline Transmission:	Earliest citation of germline transmission: J:200557
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Six2tm1(EGFP/cre)Phoh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Six2 (MGI:102778)   Mutation details: The targeting construct introduced into exon 1 an EGFP/cre fusion, IRES, puromycin resistance cassette, polyadenylation sequence, loxP site and F3-flanked neomycin resistance cassette. (J:200557)

Activity:	Tissue activity of this recombinase allele
Driver:	Six2 (mouse) Summary of all recombinase alleles driven by Six2. Alliance mouse Six2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Six2 Mutation:	15 strains or lines available

Original:	J:200557 Dolt KS, et al., A universal vector for high-efficiency multi-fragment recombineering of BACs and knock-in constructs. PLoS One. 2013;8(4):e62054
All:	2 reference(s)