Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il15tm1.1Iku
Name:	interleukin 15; targeted mutation 1.1, Koichi Ikuta
MGI ID:	MGI:5574316
Synonyms:	IL-15CFP, IL-15-CFP
Gene:	Il15  Location: Chr8:83058261-83129851 bp, - strand  Genetic Position: Chr8, 39.33 cM
Alliance:	Il15tm1.1Iku page

Germline Transmission:	Earliest citation of germline transmission: J:206571
Parent Cell Line:	KY1.1 (ES Cell)
Strain of Origin:	(C57BL/6J x 129S6/SvEvTac)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A ECFP-loxP-neo-loxP cassette was inserted at the start codon on exon 3. Cre-mediated recombinase removed the neo-cassette. Reporter expression is seen in stromal cells in various lymphoid organs. (J:206571)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il15 Mutation:	43 strains or lines available

Original:	J:206571 Cui G, et al., Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo. Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1915-20
All:	2 reference(s)