Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(TG-TPR/NTRK1)#Rstn
Name:	transgene insertion, Jay Rothstein
MGI ID:	MGI:5569754
Synonyms:	TG-Trk-T1, TRK-T1
Transgene:	Tg(TG-TPR/NTRK1)#Rstn  Location: unknown
Alliance:	Tg(TG-TPR/NTRK1)#Rstn page

Strain of Origin:

(C57BL/6 x C3H)F1

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Mutation details: This transgene contained the bovine thyroglobulin (TG) promoter and a translocation fusion product of human TPR and human NTRK1, something observed in human papillary thyroid carcinomas. Three lines were established. (# - line not specified) (J:67120)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:67120 Russell JP, et al., The TRK-T1 fusion protein induces neoplastic transformation of thyroid epithelium. Oncogene. 2000 Nov 23;19(50):5729-35
All:	4 reference(s)