Kmotm1.1Pjmi
Targeted Allele Detail
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| Symbol: |
Kmotm1.1Pjmi |
| Name: |
kynurenine 3-monooxygenase; targeted mutation 1.1, Paul J Muchowski |
| MGI ID: |
MGI:5569395 |
| Synonyms: |
Kmoflox (ex)5-NeoRdelta |
| Gene: |
Kmo Location: Chr1:175459759-175488419 bp, + strand Genetic Position: Chr1, 81.6 cM
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| Alliance: |
Kmotm1.1Pjmi page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:207199
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
C57BL/6J
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 5. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exon 5 floxed.
(J:207199)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Kmo Mutation: |
36 strains or lines available
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| Original: |
J:207199 Giorgini F, et al., Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain. J Biol Chem. 2013 Dec 20;288(51):36554-66 |
| All: |
1 reference(s) |
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Analysis Tools
