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Tg(Pomc-cre/ERT2)#Jke
Transgene Detail
Nomenclature
Symbol: Tg(Pomc-cre/ERT2)#Jke
Name: transgene insertion, Joel K Elmquist
MGI ID: MGI:5569339
Synonyms: POMC-cre:ERT2
Transgene: Tg(Pomc-cre/ERT2)#Jke  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsA cre/ERT2 fusion sequence was put under the control of Pomc regulatory elements in a transgenic construct. Microinjection of the construct resulted in generation of founder lines which were screened by crosses to reporter mice and treating progeny with tamoxifen to induce cre recombination. (J:207704)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pomc     Summary of all recombinase alleles driven by Pomc.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:207704 Berglund ED, et al., Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. J Clin Invest. 2013 Dec 2;123(12):5061-70
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory