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Gt(ROSA)26Sortm3(bglA*)Dwi
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm3(bglA*)Dwi
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Douglas J Winton
MGI ID: MGI:5555868
Synonyms: R26[CA]30SYNbglA
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm3(bglA*)Dwi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202689
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsThe targeting construct inserted into the locus an out-of frame and modified Caldocellum saccharolyticum gene that encodes a beta-glucosidase (SYNbglA) reporter gene with a CA30 dinucleotide repeat between the translational start site and remaining coding sequence. Replication slippage is required to achieve expression of the reporter. (J:202689)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
Notes
ES cell line = B6 1.1 (C57BL/6)
References
Original:  J:202689 Kozar S, et al., Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas. Cell Stem Cell. 2013 Nov 7;13(5):626-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory