Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sema4atm1.1Akum
Name:	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A; targeted mutation 1.1, Atsushi Kumanogoh
MGI ID:	MGI:5548200
Synonyms:	Wt-EGFP
Gene:	Sema4a  Location: Chr3:88343266-88368489 bp, - strand  Genetic Position: Chr3, 38.83 cM
Alliance:	Sema4atm1.1Akum page

Germline Transmission:	Earliest citation of germline transmission: J:205754
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 and 3 were replaced with a full-length cDNA fused to EGFP and followed by a floxed neomycin ressitance cassette. Flp-mediated recombination removed the selection cassette. (J:205754)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema4a Mutation:	39 strains or lines available

Original:	J:205754 Nojima S, et al., A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration. Nat Commun. 2013;4:1406
All:	3 reference(s)