Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Foxl2tm1.1(cre/ERT2)Kliu
Name:	forkhead box L2; targeted mutation 1.1, Kui Liu
MGI ID:	MGI:5548141
Synonyms:	Foxl2-CreERT2
Gene:	Foxl2  Location: Chr9:98837660-98840179 bp, + strand  Genetic Position: Chr9, 51.41 cM, cytoband E4
Alliance:	Foxl2tm1.1(cre/ERT2)Kliu page

Germline Transmission:	Earliest citation of germline transmission: J:206011
Parent Cell Line:	iTL BA1 (ES Cell)
Strain of Origin:	(C57BL/6NTac x 129S6/SvEvTac)F1

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Foxl2tm1.1(cre/ERT2)Kliu expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Foxl2 (MGI:1349428)   Mutation details: Homologous recombination was employed to insert an IRES-cre/ERT2-Frt-neo-Frt cassette 259 bp downstream of the stop codon of the Foxl2 gene. Chimeras were bred to C57BL/6 mice, and F1 animals were crossed to flp-expressing mice to delete the neo marker. (J:206011)

Activity:	Tissue activity of this recombinase allele
Driver:	Foxl2 (mouse) Summary of all recombinase alleles driven by Foxl2. Comparative matrix view of recombinase activities Alliance mouse Foxl2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxl2 Mutation:	15 strains or lines available

Original:	J:206011 Zheng W, et al., Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions. Hum Mol Genet. 2014 Feb 15;23(4):920-8
All:	6 reference(s)