Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Xcr1tm2(HBEGF/Venus)Ksho
Name:	chemokine (C motif) receptor 1; targeted mutation 2, Tsuneyasu Kaisho
MGI ID:	MGI:5544058
Synonyms:	Xcr1DTRvenus
Gene:	Xcr1  Location: Chr9:123681380-123691094 bp, - strand  Genetic Position: Chr9, 74.71 cM, cytoband F4
Alliance:	Xcr1tm2(HBEGF/Venus)Ksho page

Germline Transmission:	Earliest citation of germline transmission: J:204851
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Xcr1tm2(HBEGF/Venus)Ksho expresses 1 gene Knock-in expresses: Organism Expressed Gene Homolog in Mouse Note human HBEGF (1839) Hbegf  (MGI:96070)   Mutation details: A fusion of the human HBEGF (DTR; diphtheria toxin receptor) and Venus reporter followed by a loxP and FRT-flanked neomycin resistance cassette replaced the coding sequence. (J:204851)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Xcr1 Mutation:	32 strains or lines available

Original:	J:204851 Yamazaki C, et al., Critical roles of a dendritic cell subset expressing a chemokine receptor, XCR1. J Immunol. 2013 Jun 15;190(12):6071-82
All:	23 reference(s)