Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Msx2m1Btlr
Name:	msh homeobox 2; mutation 1, Bruce Beutler
MGI ID:	MGI:5532713
Synonyms:	duke
Gene:	Msx2  Location: Chr13:53620917-53626816 bp, - strand  Genetic Position: Chr13, 27.84 cM
Alliance:	Msx2m1Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced a G to T transversion at base pair 53468395 (v38) on Chromosome 13, equivalent to base pair 388435 in the GenBank genomic region NC_000079. The mutation corresponds to residue 648 in the NM_013601 mRNA sequence in exon 2 of 2 total exons. The mutation results in an arginine (R) to leucine (L) substitution at residue 193 (R193L). (J:204501) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Msx2 Mutation:	23 strains or lines available

Original:	J:204501 Weatherly J, et al., Direct data submission for Mutagenetix entry for duke. MGI Direct Data Submission. 2014;
All:	1 reference(s)