Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Bach2tm1.1Kuro
Name:	BTB and CNC homology, basic leucine zipper transcription factor 2; targeted mutation 1.1, Tomohiro Kurosaki
MGI ID:	MGI:5521711
Gene:	Bach2  Location: Chr4:32238804-32586108 bp, + strand  Genetic Position: Chr4, 14.02 cM, cytoband A4
Alliance:	Bach2tm1.1Kuro page

Germline Transmission:	Earliest citation of germline transmission: J:202810
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An FRT flanked neomycin resistance cassette followed by a loxP site was inserted in intron 3 and a second loxP site was inserted following exon 4. The neo selection cassette was subsequently removed from properly targeted mice by crossing to mice ubiquitously expressing flp recombinase. (J:202810)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bach2 Mutation:	44 strains or lines available

Original:	J:202810 Kometani K, et al., Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation. Immunity. 2013 Jul 25;39(1):136-47
All:	13 reference(s)