Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Vapbtm1.1Ics
Name:	vesicle-associated membrane protein, associated protein B and C; targeted mutation 1.1, Mouse Clinical Institute
MGI ID:	MGI:5521565
Synonyms:	Vapbtm1.1Ldps
Gene:	Vapb  Location: Chr2:173579378-173626132 bp, + strand  Genetic Position: Chr2, 97.37 cM, cytoband H3
Alliance:	Vapbtm1.1Ics page

Germline Transmission:	Earliest citation of germline transmission: J:198145
Parent Cell Line:	P1 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Exon 3 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:198145)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vapb Mutation:	28 strains or lines available

Original:	J:198145 Kabashi E, et al., Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis. Hum Mol Genet. 2013 Jun 15;22(12):2350-60
All:	1 reference(s)