Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Smarca5MommeD35
Name:	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5; modifier of murine metastable epialleles, D35
MGI ID:	MGI:5515388
Gene:	Smarca5  Location: Chr8:81426572-81466088 bp, - strand  Genetic Position: Chr8, 38.41 cM
Alliance:	Smarca5MommeD35 page

Strain of Origin:

FVB/N

Allele Type:    Chemically induced (ENU) (Hypomorph) Mutation:    Single point mutation   Mutation details: A A-to-G single point mutation in exon 9 is predicted to result in a N341S amino acid substitution in the encoded protein. Reduced amounts of encoded protein were detected on Western blot of embryonic tissue, suggesting that this allele is hypomorphic. (J:201508)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smarca5 Mutation:	49 strains or lines available

Original:	J:201508 Daxinger L, et al., An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Genome Biol. 2013 Sep 11;14(9):R96
All:	1 reference(s)