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Vwftm2Aird
Targeted Allele Detail
Summary
Symbol: Vwftm2Aird
Name: Von Willebrand factor; targeted mutation 2, William C Aird
MGI ID: MGI:5514147
Synonyms: vWFdeltaIntLacZ
Gene: Vwf  Location: Chr6:125529911-125663642 bp, + strand  Genetic Position: Chr6, 59.32 cM
Alliance: Vwftm2Aird page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198222
Parent Cell Line:  BK4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    A beta-galactosidase and neomycin resistance cassette replaced intron 1 through 3. (J:198222)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vwf Mutation:  139 strains or lines available
References
Original:  J:198222 Yuan L, et al., Role of RNA splicing in mediating lineage-specific expression of the von Willebrand factor gene in the endothelium. Blood. 2013 May 23;121(21):4404-12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory