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Scn3atm1Jwo
Targeted Allele Detail
Summary
Symbol: Scn3atm1Jwo
Name: sodium channel, voltage-gated, type III, alpha; targeted mutation 1, John N Wood
MGI ID: MGI:5505504
Gene: Scn3a  Location: Chr2:65288607-65397971 bp, - strand  Genetic Position: Chr2, 38.55 cM
Alliance: Scn3atm1Jwo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:199857
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting construct introduced loxP sites flanking exons 4 and 5 and a FRT-flanked neomycin resistance cassette following the second loxP site. (J:199857)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Scn3a Mutation:  110 strains or lines available
References
Original:  J:199857 Nassar MA, et al., Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. Mol Pain. 2006;2:33
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory