Slc39a4tm1e(EUCOMM)Hmgu
Targeted Allele Detail
|
Symbol: |
Slc39a4tm1e(EUCOMM)Hmgu |
Name: |
solute carrier family 39 (zinc transporter), member 4; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:5497208 |
Gene: |
Slc39a4 Location: Chr15:76496583-76501579 bp, - strand Genetic Position: Chr15, 36.16 cM
|
IMPC: |
Slc39a4 gene page |
|
Mutant Cell Lines: |
HEPD0853_5_A03, HEPD0853_5_A04, HEPD0853_5_B02, HEPD0853_5_B03, HEPD0853_5_C02, HEPD0853_5_E03, HEPD0853_5_E04, HEPD0853_5_F01, HEPD0853_5_F03, HEPD0853_5_F04, HEPD0853_5_G03, HEPD0853_5_G04, HEPD0853_5_H01 |
Germline Transmission: |
Unknown
|
Parent Cell Line: |
JM8.N4 (ES Cell)
|
Strain of Origin: |
C57BL/6N
|
Project Collection: |
EUCOMM
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutation: |
|
Insertion
Vector: L1L2_GT0_LF2A_LacZ_BetactP_neo
|
|
|
Mutation details: The L1L2_GT0_LF2A_LacZ_BetactP_neo cassette was inserted at position 76499838 of Chromosome 15 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
|
|
|
|
Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
1 reference(s) |
|