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Gt(ROSA)26Sortm18Sia
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm18Sia
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 18, Shinichi Aizawa
MGI ID: MGI:5491538
Synonyms: R26R-mCherry-hCdt1, Rosa26R-mCherry-hCdt1(30/120)
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm18Sia page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:196795
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting construct introduced a floxed STOP cassette followed by an mCherry and the ubiquitylation domains of human CDT1 (amino acids 30 to 120) fusion. (J:196795)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:196795 Abe T, et al., Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter. Development. 2013 Jan 1;140(1):237-46
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory