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Tg(CAG-Rrm2)#Rsw
Transgene Detail
Summary
Symbol: Tg(CAG-Rrm2)#Rsw
Name: transgene insertion, Robert S Weiss
MGI ID: MGI:5488606
Synonyms: Rrm2Tg
Transgene: Tg(CAG-Rrm2)#Rsw  Location: unknown  
Alliance: Tg(CAG-Rrm2)#Rsw page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-Rrm2)#Rsw expresses 1 gene
 
Mutation detailsMouse cDNA encoding Rrm2 is expressed under the control of chicken beta-actin promoter and cytomegalovirus enhancer regulatory sequences ("CAG" promoter). Two Rrm2 transgene-positive founders were generated and subsequently maintained on a pure FVB/N strain background, but these lines were not distinguished in experimental descriptions. (J:133963)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:133963 Xu X, et al., Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms. Cancer Res. 2008 Apr 15;68(8):2652-60
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory