Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(CAG-NR2F1)Mjts
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ming-Jer Tsai
MGI ID:	MGI:5474793
Synonyms:	CAG-S-hCOUP-TFI
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(CAG-NR2F1)Mjts page

Germline Transmission:	Earliest citation of germline transmission: J:162256
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Gt(ROSA)26Sortm1(CAG-NR2F1)Mjts expresses 1 gene Knock-in expresses: Organism Expressed Gene Homolog in Mouse Note human NR2F1 (7025) Nr2f1  (MGI:1352451)   Mutation details: A conditional over-expression cassette was inserted into the locus. The cassette contains a CAG promoter, floxed STOP cassette, FLAG- and myc-tagged human cDNA and polyadenylation sequence. (J:162256)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:162256 Wu SP, et al., Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo. Mol Endocrinol. 2010 Jun;24(6):1297-304
All:	3 reference(s)