Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cfl1c5
Name:	cofilin 1, non-muscle; c5
MGI ID:	MGI:5473701
Synonyms:	C5
Gene:	Cfl1  Location: Chr19:5540483-5544059 bp, + strand  Genetic Position: Chr19, 4.34 cM
Alliance:	Cfl1c5 page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU induced a T-to-A transversion leading to a p.F101I missense substitution. Western blot analysis of whole embryo lysates from homozygous mice indicates a decrease in protein expression. (J:98216, J:194042) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cfl1 Mutation:	25 strains or lines available

Original:	J:194042 Mahaffey JP, et al., Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo. Development. 2013 Mar;140(6):1262-71
All:	3 reference(s)