Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rr96tm1.1Tich
Name:	regulatory region 96; targeted mutation 1.1, Tian Chi
MGI ID:	MGI:5470225
Synonyms:	Cd*, Cd4tm1.1Tich
Gene:	Rr96  Location: unknown  Genetic Position: Chr6, Syntenic
Alliance:	Rr96tm1.1Tich page

Germline Transmission:	Earliest citation of germline transmission: J:191711
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Modified regulatory region) Mutation:    Insertion   Mutation details: A tetO sequence followed by a loxP site and then an FRT flanked neomycin selection cassette were inserted immediately upstream of the Cd4 silencer sequence in intron 1. A second loxP site was inserted immediately downstream of the silencer. The selection cassette was subsequently removed by flp recombinase expression. (J:191711)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr96 Mutation:	0 strains or lines available

Original:	J:191711 Wan M, et al., A general approach for controlling transcription and probing epigenetic mechanisms: application to the CD4 locus. J Immunol. 2013 Jan 15;190(2):737-47
All:	1 reference(s)